Poe’s tales are interwoven in one tragedy-laden narrative of a young man (Henry B. Walthall) who yearns to escape from his overbearing, one-eyed uncle (Spottiswoode Aitken). After the nephew murders the ogre, he and his lover (Blanche Sweet) are wracked by guilt and tormented by nightmares, ghosts, and demonic entities that drive them to even more horrifying extremes.