From the director of The Texas Chainsaw Massacre and producer Martin Scorsese comes this contemporary re-telling of Mary Shelley's gothic horror classic. Renowned scientist Victor Helios (Thomas Kretschmann) and his prototype creation, Deucalion (Vincent Perez) have managed to exist nearly 200 years through genetic manipulation. Now operating out of New Orleans, Helios has established a genome research institute that secretly produces a "perfect" race of people designed to replace mankind. But tortured by their own existence, the mad doctor's creations are becoming increasingly unpredictable and dangerous. Learning of his inventor's plan, Deucalion seeks help from local detectives O'Connor (Parker Posey) and Sloan (Adam Goldberg) to stop Helios from going through with his evil scheme.